In 1962 Peter Mitchell purchased Glynn House, a semi-derelict Regency-fronted mansion. He restored the building, established his laboratory there and in 1964 together with Jennifer Moyle co-founded the charitable company, Glynn Research Limited to administer and finance the Institute. The Institute was provided with an endowment of £240,000 by Peter Mitchell and his brother Christopher. The company name was later changed (in 1985) to The Glynn Research Foundation Limited. Research commenced in 1965 with four permanent members of staff - Mitchell as Research Director, Moyle as Research Fellow together with a technician and Company Secretary. Experimental work was undertaken to test the chemiosmotic hypothesis, which Mitchell had formulated at the University of Edinburgh.
By the mid-1970s the hypothesis had become widely accepted as a theory and in 1978 Mitchell received recognition for his achievements with the award of the Nobel Prize for Chemistry. Work continued at the Institute to develop the chemiosmotic theory and improve knowledge about the molecular mechanisms of energy transfer in cells. Mitchell remained Director of Research until 1987, when he became Chairman and Honorary Director of the Glynn Research Institute and Peter Rich was appointed Director of Molecular Research.
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