Catalogue description PUBLISHED PAPERS AND BIBLIOGRAPHY

1 box of published papers, and accompanying 'List of Sir Ernst Chain's publications' (compiled at Imperial College, London, August 1979).

LIST OF SIR ERNST CHAIN'S PUBLICATIONS

1. BEITRAGE ZUR ENZYMATISCHEN ESTERBILDUNG UND SPOLTUNG:

P. Rona, E. Chain & R. Ammon

Bioch. Zeitschr. (1932) 247, 113

2. ZUR KONFIGURATIONS SPECIFITAT DER ESTERSYNTHETISIERENDEN FERMENTE:

P. Rona & E. Chain

Bioch. Zeitschrift (1933) 258, 480

3. THE ISOELECTRIC POINTS OF LECITHIN & SPHINGOMYELIN:

E. Chain & I. Kemp

Biochem. J. (1934) 2052

4. THE SPONTANEOUS DECOMPOSITION OF LECITHIN & ITS BEARING ON THE DETERMINATION OF THE ISOELECTRIC POINT:

H. Fischgold & E. Chain

Biochem. J. XXVIII, No. 6 (1934) 2044-2051

5. ON THE AMPHOLYTIC NATURE OF PHOSPHOLIPINS:

H. Fischgold & E. Chain

Proc. Roy. Soc. London, Series B, No. 804 117, 239-257 (1935)

6. EFFECT OF SNAKE VENOMS ON GLYCOLYSIS & FERMENTATION IN CELL-FREE EXTRACTS:

E. Chain

Quar. J. of Exp. Physiol. 26 No. 3 (1937) 299-303

7. NEUTRALISATION OF THE ANTIFERMENTING PRINCIPLE IN SNAKE VENOMS BY ANTIVENINS:

Quart. J. Exp. Physiology (1937) 27, 49-54

E. Chain

8. STUDIES ON THE CHEMICAL NATURE OF THE ANTI FERMENTING PRINCIPLE IN BLACK TIGER SNAKE VENOM:

Quart. J. of Experimental Physiology, Vol. 27, No. 4 (Feb. 1938)

E. B. Chain & L. J. Goldsworthy

9. STUDIES ON PHOSPHORYLCHOLINE:

A. B. L. Beznak & E. Chain

Quar. J. Exp. Physiol. (1937) 26, No. 3, 201-214

10. STUDIES ON THE COLORIMETRIC DETERMINATION OF PHOSPHATE:

I. Berenblum, E. B. Chain

Biochem. J. Vol. XXXII, No. 2 (1938) 286-294

11. AN IMPROVED METHOD FOR THE COLORIMETRIC DETERMINATION OF PHOSPHATE:

1. Berenblum & E. B. Chain

Biochem. J. Vol. XXXII (1938) 295-298

12. A RETICULOCYTOGENIC AGENT FOR GUINEA-PIGS PRESENT IN CERTAIN GASTRO-INTESTINAL SECRETIONS:

J. Goodfriend, E. B. Chain & H. W. Florey

Quart. J. of Experimental Physiology & Cognate Medical Sciences, Vol. 28, No. 2 (July 1938)

13. INHIBITION OF DEHYDROGENASES BY SNAKE VENOM:

E. B. Chain

Biochem. J. Vol. XXXIII, No. 4 (1939) 407-411

14. A MUCOLYTIC ENZYME IN TESTIS EXTRACTS:

E. B. Chain, E. S. Duthie

Nature, Vol. 144 (9 Dec. 1939) 977

15. THE STUDY OF METABOLIC ACTIVITIES OF SMALL AMOUNTS OF SURVIVING TISSUES:

1. Berenblum, E. B. Chain, N. G. Heatley

Biochem. J. Vol. XXXIII, No. 1 (1939) 68-74

16. A POLYPEPTIDE RESPONSIBLE FOR SOME OF THE PHENOMENA OF ACUTE INFLAMATION:

E. S. Duthie, E. B. Chain

Brit. J. of Experimental Pathology, Vol. XX (1939) 417

17. VIII A NEW TYPE OF MICRORESPIROMETER:

N. G. Heatley, I. Berenblum, E. B. Chain

Biochem. J. Vol. XXXIII, No. 1 (1939) 53-67

18. IDENTITY OF HYALURONIDASE & SPREADING FACTOR:

E. B. Chain, E. S. Duthie

Br. J. of Experimental Pathology, Vol. XXI (1940) 324

19. PENICILLIN AS A CHEMOTHERAPEUTIC AGENT:

E. B. Chain, H. W. Florey, A. D. Gardner, N. G. Heatley, M. A. Jennings, J. Orr-Ewing, A. G. Sanders

The Lancet (24 August 1940) 226

20. AN ENZYME FROM BACTERIA ABLE TO DESTROY PENICILLIN:

E. P. Abraham, E. Chain

Nature (1940) 146, 837

21. CARBOHYDRATE METABOLISM OF TUMOURS:

1. Berenblum, E. B. Chain, N. G. Heatley

Nature, Vol. 145 (18/5/1940) 778

22. THE METABOLISM OF NORMAL & NEOPLASTIC SKIN EPITHELIUM:

Evidence against the theory that Aerobic Glycolysis associated with a low R.Q. is a feature of a Disturbed Metabolism indicative of a Tumour growth.

1. Berenblum, E. B. Chain, N. G. Heatley

American Jour. of Cancer, Vol. XXXVIII, No. 3 (March 1940)

23. SOME OBSERVATIONS ON THE PREPARATION AND PROPERTIES OF THE SUBSTRATE OF LYSOZYME:

L. A. Epstein, E. Chain

Brit. J. Exp. Path. (1940) 21, 339

24. FURTHER OBSERVATIONS ON PENICILLIN:

E. P. Abraham, E. Chain, C. M. Fletcher, A. D. Gardner, N. G. Heatley, M. A. Jennings, H. W. Florey

Lancet (1941) 177-

25. AN ANTIBACTERIAL SUBSTANCE PRODUCED BY PENICILLIUM CLAVIFORME:

E. Chain, H. W. Florey, M. A. Jennings

Brit. J. Exp. Path (1942) 23, 202

26. THE NITROGENOUS NATURE OF PENICILLIN:

E. P. Abraham, W. Baker, E. Chain, H. W. Florey, E. R. Holiday, R. Robinson.

Nature (1942) 149, 356

27. PURIFICATION AND SOME PHYSICAL & CHEMICAL PROPERTIES OF PENICILLIN:

E. P. Abraham, E. Chain

Brit. J. Exp. Path. (1942) 23, 103

28. PROACTINOMYCIN, A BACTERIOSTATIC PRODUCED BY A SPECIES OF PROACTINOMYCES:

A. D. Gardner, E. Chain.

Brit. J. Exp. Path (1942) 23, 123

29. HELVOLIC ACID, AN ANTIBIOTIC PRODUCED BY A. FUMIGATUS:

E. Chain, H. W. Florey, M. A. Jennings, T. I. Williams

Brit. J. Exp. Path (1943) 24, 108.

30. PENICILLAMINE, A CHARACTERISTIC DEGRADATION PRODUCT OF PENICILLIN:

E. P. Abraham, E. Chain, W. Baker, R. Robinson

Nature (1943) 151, 107

31. ANTIBACTERIAL SUBSTANCES PRODUCED BY BACTERIA & FUNGI (2) (Biochemistry)

E. Chain, H. W. Florey

Annual Reports of the Chemical Society (1944) 40.

32. PENICILLIN:

E. Chain, H. W. Florey

Endeavour (1944) Vol. III, No. 9.

33. IDENTITY OF PATULIN & CLAMFORMIN:

E. Chain, H. W. Florey, M. A. Jennings.

Lancet (1944) Series 1, 112

34. BACTERICIDAL & BACTERIOLYTIC ACTION OF PENICILLIN ON THE STAPHYLOCOCCUS:

E. Chain, E. S. Duthie

Lancet (1945) 652.

35. THE CHEMICAL STRUCTURE OF THE PENICILLINS: NOBEL LECTURE

E. B. Chain

Stockholm (20 March 1946)

36. LA CONSTITOZIONE CHIMICA DELLA PENICILLINA:

E. B. Chain

Roma (1947) Vol. X

Congress at Instituto Superiore di Sanita

37. LA PENICILLINA: PROPRIETA CHIMICHE, BIOLOGICHE E TERAPEUTICHE:

E. B. Chain

Congress of the Instituto Superiore di Sanita. (1947)

38. THE CHEMISTRY OF PENICILLIN (1948):

E. B. Chain

Annual Review of Biochemistry (1948) 657-704.

39. INDUSTRIAL MICROBIOLOGY:

E. Chain

Research (1952) 5 567-576.

40. AERATION STUDIES 1. Factors influencing aeration efficiency:

1 E. B. Chain, D. S. Callow, F. Ugolini, S. Palodino, J. van de Sluis (Bulletin of W.H.O. (1952) 6, 73-97)

41. OBSERVATIONS ON PENICILLIUM CHRYSOGENUM IN SUBMERGED CULTURE:

1. Mycelial Growth & Autolysis.

L. Comici, G. Sermonti, E. B. Chain

Bulletin of World Health Organization (1952) 6, 265-276.

42. A MICROMETHOD FOR THE SERIAL DETERMINATION OF ORGANICALLY BOUND HALOGEN:

S. J. Pirt, E. B. Chain

Biochem. J. Vol. 50, No. 5 (1952) 716-719.

43. MICROBIOLOGY IN INDUSTRY:

Dr. E. B. Chain

Times Review of Industry (March 1953)

44. THE BIOCHEMICAL APPROACH TO BIOLOGICAL PHENOMENA:

Harben Lectures 1954

E. B. Chain

J. of Royal Institute of Public Health & Hygiene (May, June, Sept. 1966)

45. THE DEVELOPMENT OF BACTERIAL CHEMOTHERAPY:

Paul Ehrlich Lecture

E. B. Chain

International Record of Medical & General Practice Clinics, Vol. 167, No. 3 (March 1954)

Antibiotics & Chemotherapy 3-215 (1954)

46. AERATION STUDIES II:

Rend. Inst. Superiore, Sanita (1954) 17, 5

E. B. Chain & G. Gualandi.

47. BIOSYNTHETIC MECHANISMS OF THE FORMATION OF ORGANIC ACIDS IN MOULDS:

E. B. Chain

Proceedings of the International Congress of Biochemistry, Brussels (1955)

48. LA FIGURA E L'OPERA DI ALEXANDER FLEMING:

Prof. E. B. Chain

Nuova Antologia, Estratto-Anno 90, Vol. 464, fasc. 1853 (May 1955) 47.

49. A LABORATORY FERMENTER FOR VORTEX & SPARGER AERATION (1955):

E. B. Chain, S. Paladino, F. Ugolini, D. S. Callow, J. van der Sluis Instituto Superiore di Sanita, Vol. XVII (1955) 61-86

50. INTERRELATION OF PROTEIN & POLYNUCLEOTIDE SYNTHESIS IN ESCHERICHIA COLI:

R. Cavanna, E. B. Chain, C. G. Heden, B. Malmaren, N. A. Eliasson, E. Hammersten, S. Aqvist.

Instituto Superiore di Sanita, Vol. XVII (1955)

51. THE EFFECT OF MECHANICAL AGITATION ON THE MORPHOLOGY OF PENICILLIUM CHRYSOGENUM GROWN IN STIRRED FERMENTERS (1955):

W. M. Dion, A. Carilli, G. Sermonti., E. B. Chain

Instituto Superiore di Sanita, Vol. XVII (1955)

52. FERMENTERS OF 90 + 300 I CAPACITY FOR VORTEX & SPARGER AERATION (1955):

S. Paladino, F. Ugolini, E. B. Chain

Instituto Superiore di Sanita, Vol. XVII (1955)

53. QUANTITATIVE BIDIMENSIONAL RADIOCHROMATOGRAPHY:

E. B. Chain, M. Frank, F. Pocchiari, C. Rossi, F. Ugolini, G. Ugolini.

Instituto Superiore di Sanita, Vol. 1, Part II (1956) 241-280.

54. CARBOHYDRATE METABOLISM IN RAT LIVER:

II Glycogen & fatty acid synthesis from glucose in perfused rat liver

A. Beloff-Chain, D. Bovet, R. Catanzarro, E. B. Chain, R. Kohn, I. Masi & F. Pocchiari.

Instituto Superiore di Sanita (1956) Vol. II, Part I, 304-327.

55. EXPERIMENTS DESIGNED TO TEST THE "HEXOKINASE THEORY & PERMEABILITY THEORY" OF THE MODE OF ACTION OF INSULIN:

A. Beloff-Chain, R. Catanzarro, E. B. Chain, I. Masi & F. Pocchiari Instituto Superiore di Sanita (1956) Vol. 1, Part III.

56. CHEMISTRY & BIOCHEMISTRY OF ANTIBIOTICS:

E. B. Chain

Annual Review of Biochemistry, Vol. 27 (1958):

57. RECENT STUDIES ON CARBOHYDRATE METABOLISM:

E. B. Chain

Brit. Medical J. (17 Oct. 1959) Vol. II, 709-719.

58. SOME OBSERVATIONS ON THE MODE OF ACTION OF INSULIN:

E. B. Chain

Instituto Superiore di Sanita (1959)

59. NOTE ON THE STERILIZATION OF MEDIA CONTAINING SOLID ORGANIC MATERIAL IN LABORATORY & PILOT PLANT FERMENTERS:

E. B. Chain, S. Paladino, F. Zanchi.

Instituto Superiore di Sanita, Vol. II, Part I (1959) 88-98

60. THE DISTRIBUTION OF SULPHURYLICHOLINE IN FUNGI:

A. Ballio, E. B. Chain, F. Dentice di Accadio, F. Navazio, C. Rossi, M. Ventura Instituto Superiore di Sanita, Vol. II, Part I (1959), Roma.

61. THE FATE OF³5 S-SULPHATE & ³5 S-METHIONINE IN A HIGH YIELDING & A NONPENICILLIN PRODUCING STRAIN OF PENICILLIUM CHRYSOGENUM GROWN IN A SIMPLE REPLACEMENT MEDIUM:

A. Ballio, E. Brandl, E. B. Chain, F. Dentice di Accadia, F. Navazio, C. Rossi

Instituto Superiore di Sanita, Vol. II, Part II (1959)

62. GLUCOSE OXIDATION IN RAT BROWN ADIPOSE TISSUE HOMOGENATE:

A. Beloff-Chain, R. Catanzarro, E. B. Chain, F. Pocchiari

Instituto Superiore di Sanita, Vol. II, Part I (1959) 132-138.

63. THE METABOLISM OF PYRUVATE IN RAT LIVER & BRAIN SLICES:

A. Beloff-Chain, R. Catanzarro, E. B. Chain, I. Masi, F. Pocchiari

Instituto Superiore di Sanita, Vol. II, Part I (1959)

64. SIMPLE MEDIA FOR PENICILLIN PRODUCTION:

E. Brandl, A. Carilli, E. B. Chain

Instituto Superiore di Sanita, Vol. II, Part II (1959) 195-211.

65. PENICILLIN PRODUCTION BY WASHED MYCELIUM OF PENICILLIN CHRYSOGENUM IN REPLACEMENT MEDIA:

E. Brandl, A. Carilli, E. B. Chain

Instituto Superiore di Sanita, Vol. II, Part II (1959)

66. THE EFFECT OF MECHANICAL AGITATION ON THE PRODUCTION OF KOJIC ACID BY ASPERGINUS FLAVUS IN SUBMERGED CULTURE:

Anna Camposano, E. B. Chain, G. Gualandi.

Instituto Superiore di Sanita, Vol. II, Part II (1959)

67. AN IMPROVED AUTOMATIC SCANNER FOR THE QUANTITATIVE EVALUATION OF BIDIMENSIONAL RADIOCHROMATOGRAMS:

M. Frank

Addendum in performance by E. B. Chain, F. Pocchiari, C. Rossi

Instituto Superiore di Sanita, Vol. II, Part II (1959)

68. AUTOMATIC CONTINUOUS MEASURE & CONTROL OF pH BY MEANS OF STEAM STERILIZABLE GLASS ELECTRODES:

G. Gualandi, Elizabetta Caldarola, E. B. Chain

Instituto Superiore di Sanita, Vol. II, Part I (1959)

69. CONTINUOUS MEASURE OF DISSOLVED OXYGEN IN FERMENTATIONS IN THE PRESENCE OF MICRO-ORGANISMS:

G. Gualandi, G. Morisi, G. Ugolini, E. B. Chain

Instituto Superiore di Sanita, Vol. II, Part I (1959)

70. THE FATE OF 2-¹4-C-LABELLED ACETATE IN PENICILLIUM CHRYSOGENUM:

J. A. Olson, E. B. Chain

Instituto Superiore di Sanita, Vol. II, Part II (1959)

71. ORGANIC ACID METABOLISM OF ACETATE GROWN PENICILLIUM CHRYSOGENUM:

J. A. Olson, E. B. Chain

Instituto Superiore di Sanita, Vol. II, Part II (1959)

72. A MODIFIED "ROTATING DRUM" FERMENTER:

F. Ugolini, G. Ugolini, E. B. Chain

Instituto Superiore di Sanita, Vol. II, Part I (1959)

73. NOUVELLES VOIES MICROBIOLOGIQUES POUR L'OBTENTION DE MEDICAMENTS:

E. B. Chain

Journees Pharmaceutiques Francaises (1960)

74. PARTICIPATION OF THE AMMONIUM ION IN THE TRANSFORMATION OF GLUCOSE TO AMINO ACIDS IN BRAIN TISSUE:

E. B. Chain, M. Chiozzotto, F. Pocchiari, C. Rossi, R. Sandman

Proceedings of Roy. Soc. Vol. 152 (1960) 290-297

75. THE FATE OF GLUCOSE IN DIFFERENT PARTS OF THE RABBIT BRAIN:

E. B. Chain, S. Larsson, F. Pocchiari

Proceedings of Roy Soc. B. Vol. 152 (1960) 283-289.

76. THE ABSORPTION OF SUCROSE, MALTOSE & HIGHER OLIGOSACCHARIDES FROM THE ISOLATED RAT SMALL INTESTINE:

E. B. Chain, K. R. L. Mansford, F. Pocchiari

J. Physiol. (1960) 154, 39-51

77. LA STERILIZZAZIONE DEI TERRENI DI CULTURA CONTENUTI MATERIALE ORGANICO SOLIDO IN FERMENTATORI DA LABORATORIO E DA IMPIANTO PILOTA:

E. B. Chain, S. Paladino, F. Zanchi

Rome (1960) Vol. XXIII

Estratto dai rendiconti dell Instituto Superiore di Santa.

78. INCORPORATION OF L.W. DICARBOXYLIC ACIDS AS SIDE CHAINS INTO THE PENICILLIN MOLECULE:

A. Ballio, E. B. Chain, F. Dentice di Accadia, M. Mastropietro-Cancellieri, G. Morpurgo, G. Serlupi-Crescenzi, G. Sermonti

Nature, Vol. 185, No. 4706 (9 Jan. 1960) 97-99

79. INFLUENCE OF ANAEROBIOSIS ON GLUCOSE METABOLISM IN THE ISOLATED RAT DIAPHRAGM MUSCLE:

A. Beloff-Chain, R. Cantanzaro, E. B. Chain, L. Longinotti, I. Masi, F. Pocchiari

Drug Research 10 (1960) 330-333

80. BACTERIOLOGICAL STUDIES ON A NEW PENICILLIN BRL 1241:

G. N. Rolinson, Shirley Stevens, J. Cameron-Wood, E. B. Chain, F. R. Batchelor

Lancet, (10 Sept. 1960) 564-567.

81. MODIFIED PENICILLINS:

E. B. Chain

Laboratory Practice (1961) 238-239.

82. PRODUCTION OF LYSERGIC ACID DERIVATIVES BY A STRAIN OF CLAVICEPS PASPALI STEVENS & HALL IN SUBMERGED CULTURE:

F. Arcamone, C. Bonino, E. B. Chain, A. Ferretti, P. Pennella, A. Tonolo, Lidia Vero.

Nature, Vol. 187, No. 4733 (1961) 238-239

83. FORMATION OF 2, 3-DIHYDROXYBENZOIC ACID IN FERMENTATION LIQUORS DURING THE SUBMERGED CULTURE PRODUCTION OF LYSERGIC ACID AND HYDROXYETHYLAMIDE BY CLAVICEPS PASPALI STEVENS & HALL:

A. Arcamone, E. B. Chain, A. Ferretti, P. Pennella.

Nature, Vol. 192, No. 4802 (11 Nov. 1961) 552-553.

84. PRODUCTION OF A NEW LYSERGIC ACID DERIVATIVE IN SUBMERGED CULTURE BY A STRAIN OF CLAVICEPS PASPALI (STEVENS & HALL):

F. Arcamone, E. B. Chain, A. Ferretti, A. Minghetti, P. Pennella, A. Tonola, Lydia Vero.

Proceedings of the Roy. Soc. B. Vol. 155 (1961) 26-54.

85. IDENTIFICATION OF A COMPOUND RELATED TO 6-AMINOPENICILLANIC ACID ISOLATED FROM CULTURE MEDIA OF PENICILLIUM CHRYSOGENUM:

A. Ballio, E. B. Chain, F. Dentice di Accadia, M. , K. Rauer, M. Schlesinger, Sandra Schlesinger.

Nature, Vol. 191, No. 4791 (26 Aug. 1961) 909-910.

86. 1. 6-AMINOPENICILLANIC ACID IN PENICILLIN FERMENTATIONS:

F. R. Batchelor, E. B. Chain, G. N. Rolinson

Proceedings of Roy. Soc. B. Vol. 154 (1961) 478-489

87. III. ISOLATION & PURIFICATION OF 6-AMINOPENICILLANIC ACID:

F. R. Batchelor, E. B. Chain, T. L. Hardy, K. R. L. Mansford, G. N. Rolinson

Proceedings of Ray. Soc. B (1961) 498-508

88. V. 6-AMINOPENICILLANIC ACID AS A SUBSTITUTE FOR PENICILLANASE & AN INDUCER OF PENICILLANASE FORMATION:

F. R. Batchelor, J. Cameron-Wood, E. B. Chain, G. N. Rolinson

Proceedings of Roy. Soc. B. (1961) 514-521.

89. VI. FORMATION OF 6-AMINOPENICILLANICACID FROM PENICILLIN BY ENZYMIC HYDROLYSIS:

F. R. Batchelor, E. B. Chain, M. Richards, G. N. Rolinson.

Proceedings of Roy. Soc. B. (1961) 522-531.

90. AERATION STUDIES. CONTINUOUS MEASUREMENT OF DISSOLVED OXYGEN DURING FERMENTATION IN LARGE FERMENTERS:

A. Carilli, E. B. Chain, G. Gualandi, G. Morisi

Sci. Repts. Instituto Superiore di Sanita (1961) 177-189.

91. ACTION OF INSULIN ON METABOLIC REACTIONS:

(CIBA Foundation Symposium on Enzymes and Drug Action 1962)

E. B. Chain

Instituto Superiore di Sanita, pp. 95-109 of above Symposium notes.

92. STUDIES ON BRAIN METABOLISM - Chap II:

E. B. Chain

Ultrastructure & Metabolism of the Nervous System, Vol. XL (1962) 27-42.

93. INTER-RELATION OF GLUCOSE, GLUTAMATE, & ASPARTATE METABOLISM IN RAT CEREBRAL CORTICAL SLICES:

E. B. Chain, M. M. Cohen, F. Pocchiari

Proceedings of Roy. Soc. B. Vol. 156 (1962) 163-167.

94. THE METABOLISM OF GLUTAMIC ACID IN RAT RETINA:

E. B. Chain, F. Pocchiari, H. W. Reading.

Proceedings of Roy. Soc. B. Vol. 156 (1962) 144-147.

95. THE EFFECT OF TRYTOPHAN & METHYLTRYPTOPHANS ON SUBMERGED LYSERGIC ACID FERMENTATION BY CLAVICEPS PASPALI (STEVENS & HALL) 1957:

F. Arcamone, E. B. Chain, A. Ferretti, A. Minghetti, P. Pennella, A. Tonolo.

Biochem., Biophys. Acta. 57 (1962) 174-176.

96. THE INFLUENCE OF GLUCOSE ON ACETATE ALANINE & PRYUVATE METABOLISM IN RAT CEREBRAL CORTICAL SLICES:

A. Beloff-Chain, Rafaella Catonzaro, E. B. Chain, L. Longinotti, Ines Masi, F. Pocchiari

Proceedings of Roy. Soc. B. Vol. 156 (1962) 168-171.

97. THE METABOLISM OF GLUCOSE & PYRUVATE IN RAT RETINA:

R. Catanzaro, E. B. Chain, F. Pocchiari, H. W. Reading

Proceedings of the Roy. Soc. B. Vol. 156 (1962) 139-143.

98. THE METABOLISM OF GLUTAMATE & ASPARTATE IN RAT CEREBRAL CORTICAL SLICES:

O. Z. Sellinger, R. Catanzaro, E. B. Chain, F. Pocchiari

Proceedings of Roy. Soc. B. Vol. 156 (1962) 148-162.

99. ACADEMIC & INDUSTRIAL CONTRIBUTIONS TO DRUG RESEARCH:

Trueman Wood Lecture

E. B. Chain

English: Nature, Vol. 200, No. 4905 (Nov. 1963) 441-451

Swedish: Nytt och Nyttigt, Nr. 2 (1966

French: Medecine et Hygiene, No. 675 (17 Feb. 1964)

German: Arzneimitte-Forschung 13, 829-841.

100. CONTRIBUTI DELLA FONDAZIONE WELLCOME ALLA RICERA SCIENTIFICA NEL CAMPO DELLA MEDECINA:

E. B. Chain (1963) Wellcome Italia.

101. PURE & APPLIED CHEMISTRY:

E. B. Chain

Journal of International Union of Pure & Applied Chemistry, Vol. 6 (1963) 483-491.

102. STUDIES ON FERROVERDIN, A GREEN IRON-CONTAINING PIGMENT PRODUCED BY A STREPTOMYCES WAK SPECIES (1963:)

Proceedings of Roy. Soc. B. Vol. 158 (1963) 43-70.

A. Ballio, H. Bertholdt. A. Carilli, E. B. Chain, V. di Vittorio, A. Tonolo, Lidia Vero Barcellona.

Proceedings of Roy. Soc. B. Vol. 158 (1963) 43-70.

103. STUDIES ON PENICILLINASE PRODUCED BY A STRAIN OF STAPHYLOCOCCUS AUREUS:

F. R. Batchelor, J. Cameron-Wood, E. B. Chain, G. N. Rolinson

Proceedings of Roy. Soc. B. Vol. 158 (1963) 311-328.

104. CONQUEST OF THE RESISTANT STAPHYLOCOCCUS BY NEW PENICILLINS:

E. B. Chain

New Scientist, Vol. 8 (1964) 838-840.

105. NEW ANTIBIOTICS (The New Penicillins):

E. B. Chain

New Perspectives in Biology - BBA Lib. Vol. 4 (1964) Elsevier Publishing Co.

106. THE NEW PENICILLINS:

E. B. Chain

Laboratory Aspects of Therapy (reprinted from Therapy with the New Penicillins) (Conf. at Apothecaries Hall June 1964)

107. DEVELOPMENT & TRENDS OF ANTIBIOTIC RESEARCH

Oliver Sharpey Lecture

E. B. Chain

Proceedings of Conference at Royal College of Physicians (16-29 Nov. 1964)

108. FUSICOCCIN: A NEW WILTING TOXIN PRODUCED BY FUSICOCCUM AMYGDALI - DEL

E. B. Chain, A, Ballio, P. de Leo, B. F. Erlanger, M. Mauri, A. Tonolo.

Nature, Vol. 203, No. 4942 (18 July 1964) 297.

109. ANTI-BACTERIAL CHEMOTHERAPY

Mary Barber, E. B. Chain

Annual Review of Pharmacology, Vol. 4 (1964)

110. THE METABOLISM OF GLUCOSE. 1. PHOSPHATE & GLUCOSE. 6. PHOSPHATE & THEIR INFLUENCE ON THE METABOLISM OF GLUCOSE IN RAT DIAPHRAGM MUSCLE

A. Beloff-Chain, P. Betto, Raffaella Catanzaro, E. B. Chain, L. Longinotti, I. Masi, F. Pocchiari

Biochem. J. (1964) 91, 620

111. JEPHCOTT LECTURE

Contributions from Chemical Microbiology to Therapeutic Medicine

E. B. Chain

Proceedings of Roy. Soc. of Medicine, Vol. 58 (Feb. 1965) No. 2, 85-96.

112. LANDMARKS & PERSPECTIVES IN BIOCHEMICAL RESEARCH

(Inaugural Lecture)

E. B. Chain

B.M.F.(23 & 30 Jan. 1965) 1, 209-220 & 273-278.

113. PHASES OF PENICILLIN RESEARCH (1965)

E. B. Chain

Israel Journal of Medical Sciences, Vol. 1, No. 6 (Nov. 1965) 1400-1405.

114. USE OF RADIOISOTOPES IN GENERAL BIOCHEMISTRY

E. B. Chain

Chemistry & Industry (1965) 1352-1353.

115. TWENTY-FIVE YEARS OF PENICILLIN THERAPY IN PERSPECTIVE

E. B. Chain

Antimicrobial agents & Chemotherapy (1965)

116. EFFECT OF AMMONIUM & OTHER IONS ON THE GLUCOSE-DEPENDENT ACTIVE TRANSPORT OF L-HIST ADINE IN SLICES OF RAT BRAIN CORTEX

D. F. de Almeida, E. B. Chain, F. Pocchiari

Biochem. J. (1965) 95, 793-796.

117. A NITROSOPHENOLCOBALT CHELATE PRODUCED BY A STREPTOMYCETE

A. Ballio, S. Barcellona, E. B. Chain, A. Tonolo, Lidia Vero-Barcellona.

Proceedings of Roy. Soc. B. Vol. 161 (1965) 384-391.

118. INFLUENCE OF SOME MONONUCLEOTIDES & THEIR CORRESPONDING NUCLEOSIDES ON THE MET. OF CARBOHYDRATES IN THE ISOLATED RAT DIAPHRAGM MUSCLE

A. Beloff-Chain, P. Betto, W. Bleszynski, Raffaella Catanzaro, E. B. Chain, A. A. Dmitrovski, L. Longinotti, F. Pocchiari.

Biochem. J. (1965) 97, 565-568.

119. AERATION STUDIES IV

Aeration Conditions in 3000-litre submerged Fermentation with various Micro-organisms.

E. B. Chain, G. Gualandi, G. Morisi

Biotechnology & Bio-Engineering Vol. VIII (1966) 595-619.

120. THE QUEST FOR NEW BIODYNAMIC SUBSTANCES

E. B. Chain

Perspectives in Biology & Medicine, Vol. 10, No. 2 (1967)

121. STUDIES CONCERNING LYSERGIC & DIHYDROLYSERGIC ACID & HYDROXYETHYLAMIDES

F. Arcamone, B. Camerino, E. B. Chain, A. Ferretti, S. Redailli

Tetrahedron (1967), Vol. 23, 11-18 Pub. Pergammon Press

122. INFLUENCE OF ANTI-INSULIN SERUM ON GLUCOSE METABOLISM (1) IN ISOLATED ADIPOSE TISSUE

A. Beloff-Chain, R. Catanzaro, E. B. Chain

Diabetes (July 1967) Vol. 16, No. 7, 472-474.

123. VIRUSES IN FUNGI & INTERFERON STIMULATION

G. T. Banks, K. W. Buck, E. B. Chain, F. Himmelweit, J. E. Marks, J. M. Tyler, M. Hollings, F. T. Last, O. M. Stone

Nature, Vol. 218, No. 5141 (11 May 1968) 542-545.

124. THE CONSTITUTION OF FUSICOCCIN

K. D. Barrow, D. H. R. Barton, E. B. Chain, U. F. W. Ohnsorge, R. Thomas Chemical Communications (1968)

125. FUSIOCOCCIN: CHARACTERISATION OF THE OXYGEN SUBSTITUENTS

K. D. Barrow, D. H. R. Barton, E. B. Chain, C. Conlay, T. V. Smale, R. Thomas, E. S. Waight.

Chemical Communications (1968)

126. FORMATION & STRUCTURE OF EXTRACELLULAR GLUCANS PRODUCED BY CLAVICEPS SPECIES

K. W. Buck, A. W. Chen, A. G. Dickerson, E. B. Chain

J. Gen. Microbiol. (1968) 51, 337-352.

127. EFFECTS OF INSULIN ON THE PATTERN OF GLUCOSE METABOLISM IN THE PERFUSED WORKING & LANGENDORFF HEART OF NORMAL & INSULIN DEFICIENT RATS

E. B. Chain, K. R. L. Mansford, L. H. Opie

Biochem, J. (1969) 115, 537.

128. METABOLISM OF HEXOSES IN RAT CEREBRAL CORTEX SLICES

E. B. Chain, S. P. R. Rose, I. Masi, F. Pocchiari

J. Neurochem. (1969) 16, 93-100.

129. PENICILLIUM CYANEO-FULVUM VIRUS & INTERFERON STIMULATION

G. T. Banks, K. W. Buck, E. B. Chain, Joan E. Darbyshire, F. Himmelweit. Nature, Vol. 223, No. 5202 (12 July 1969) 155-158.

130. VIRUS-LIKE PARTICLES IN PENICILLIN PRODUCING STRAINS OF PENICILLIUM CHRYSOGENUM

G. T. Banks, K. W. Buck, E. B. Chain, Joan Darbyshire, F. Himmelweit. Nature, Vol. 222, No. 5188 (5 Apr. 1969) 89-90.

131. GLOCOSE & AMINO-ACID METABOLISM IN SOME INVERTEBRATE NERVOUS SYSTEMS

H. F. Bradford, E. B. Chain, H. T. Cory, S. P. R. Rose

J. of Neurochemistry (1969) Vol. 16, 969-978.

132. HIGH CELL WALL GALACTOSAMINE CONTENT & VIRUS PARTICLES IN PENICILLIUM STOLONIFERUM

K. W. Buck, E. B. Chain, Joan Darbyshire

Nature (1969) 233, 1273.

133. THE BIOCHEMIST'S APPROACH TO MEDICAL RESEARCH

E. B. Chain

The Scientific Basis of Medicine Annual Reviews (1970)

134. RECENT STUDIES IN AMINO ACID GLUCOSE INTERRELATIONS IN BRAIN

E. B. Chain

FEBS Symposium, Vol. 21 (1970) 306-319.

135. SOCIAL RESPONSIBILITY & THE SCIENTIST IN MODERN WESTERN SOCIETY

Robert Waley Cohen Memorial Lecture.

Prof. Sir E. Chain

The Council of Christians & Jews (1970)

136. SOCIAL RESPONSIBILITY & THE SCIENTIST

Prof. Sir E. Chain

New Scientist (1970) 22, 166-170.

137. A COMPUTERISED SCANNER FOR BIDIMENSIONAL RADIOCHROMATOGRAMS

E. B. Chain, A. E. Lowe, K. R. L. Mansford

J. of Chromatography, 53 (1970) 293-314.

138 ANTIVIRAL ACTIVITY OF DOUBLE STRANDED RNA FROM A VIRUS ISOLATED FROM ASPERGILLUS FOETIDUS

G. T. Banks, K. W. Buck, E. B. Chain, Joan E. Darbyshire, F. Himmelweit, G. Ratti, T. J. Sharpe, D. N. Planterose

Nature, Vol. 227, No. 5257 (Aug. 1, 1970) 505-507.

139. INFLUENCE OF INSULIN ON THE MET. OF GLUCOSAMINE IN THE ISOLATED RAT DIAPHRAGM MUSCLE

A. Beloff-Chain, E. B. Chain, K. A. Rookledge

Biochem. J. (1970) 119, 27-30.

140. BIOSYNTHESIS OF N--HYDROXYETHYL) LYSERGAMIDE, A METABOLITE OF CLAVICEPS PASPALI (STEVENS & HALL)

N. Castagnoli, Jun., K. Corbett, E. B. Chain, R. Thomas

Biochem. J. (1970) 117, 451-455.

141. FURTHER INVESTIGATIONS OF THE TOXICITY OF FUSIOCOCCINS

E. B. Chain, P. G. Mantle, B. V. Milborrow

Physiological Plant Pathology (1971) 1, 495-514.

142. FUSICOCCIN. PART I. THE NATURE OF THE SUBSTITUENT GROUPS

K. D. Barrow, D. H. R. Barton, Sir Ernst Chain, C. Conlay, T. C. Smale, R. Thomas, E. S. Wright.

J. of the Chemical Soc., Section C, Organic Chemistry (1971)

143. FUSICOCCIN. PART II. THE CONSTITUTION OF FUSICOCCIN

K. D. Barrow, D. H. R. Barton, Sir Ernst Chain, U. F. W. Ohnsorge, R. Thomas J. of the Chemical Soc., Section C, Organic Chemistry (1971)

144. THE INFLUENCE OF INSULIN & OF CONTRACTION ON GLUCOSE METABOLISM IN THE PERFUSED DIAPHRAGM MUSCLE FROM NORMAL & STREPTOZOTOCIN-TREATED RATS

A. Beloff-Chain, E. B. Chain, K. A. Rookledge

Biochem. J. (1971) 125, 97-103.

145. COMPARISON OF INTERFERON INDUCTION IN MICE BY PURIFIED PENICILLIUM CHRYSOGENUM VIRUS & DERIVED DOUBLE-STRANDED RNA

K. W. Buck, E. B. Chain, F. Himmelweit

Journal of General Virology (1971) 12, 131-139.

146. PSEUDOMONIC ACID: AN ANTIBIOTIC PRODUCED BY PSEUDOMONAS FLUORESCENS

A. T. Fuller, G. Mellows, M. Woolford, G. T. Banks, K. D. Barrow, E. B. Chain Nature, Vol. 234, No. 5329 (1971) 416-417.

147. CRYSTAL PROTEIN OF BACILLUS THURINGIENSIS VAR. TOLWORTHI

Subunit Structure & Toxicity to Pieris brassicae.

Barry N. Herbert, Hannah J. Gould, Ernst B. Chain

Eur. J. Biochem 24 (1971) 366-375.

148. FUNGAL VIRUSES & THEIR ANTIVIRAL PROPERTIES

Sir Ernst Chain

Proc. Roy. Inst. 45 (1972)

149. THIRTY YEARS OF PENICILLIN THERAPY

Sir Ernst Chain

J. Roy. Coll. Phycns. Lond. Vol. 6, No. 2 (2 January 1972) also Proc. R. Soc. Lond. B. (1971) 179, 293-319.

150. INVESTIGATIONS ON THE PHYTOTOXICITY OF FUSICOCCINS

Sir Ernst Chain, Peter G. Mantle, Barry V. Milborrow (1972)

In Phytotoxins in Plant Diseases

Ed. R. K. S. Wood, A. Ballio, A. Graniti Academic Press.

151. EFFECT OF GLUCOSE ON ENZYME RELEASE FROM, AND RECOVERY OF, THE ANOXIC MYOCARDIUM

D. J. Hearse & E. B. Chain

In: Myocardial Metabolism: Recent Advances in Studies on Cardiac Structure & Metabolism (1972) Vol. 3. University Park Press, Baltimore, P.763-772

152. GLUCOSE & THE SURVIVAL & RECOVERY OF THE ANOXIC MYOCARDIUM

D. J. Hearse & E. B. Chain

Proceedings of the Biochemical Society Biochem. J. (1972) 127, No. 2, 20 P

153. THE ROLE OF GLUCOSE IN THE SURVIVAL & 'RECOVERY' OF THE ANOXIC ISOLATED PERFUSED RAT HEART

D. J. Hearse & E. B. Chain

Biochem. J. (1972) 128, 1125-1133.

154. PROFESSOR HEYMAN'S MEMORIAL SPEECH:

Ernst Chain

Archives Internationales de Pharmacodynami et de Therapie Supplementum to Vol. 202 (April 1973)

155. RELATIONSHIPS BETWEEN INDUSTRIAL & ACADEMIC LABORATORIES:

E. Chain

Biochem. Soc. Spec. Publ. (1973) 2, 51-56.

156. PROTEIN SYNTHESIS BY PERFUSED HEARTS FROM NORMAL & INSULIN-DEFICIENT RATS:

Ernst B. Chain & Peter M. Sender

Biochem. J. (1973) 132, 593-601.

157. FUSICOCCIN. PART III. THE STRUCTURE OF FUSICOCCIN H:

K. D. Barrow, D. H. R. Barton, Sir Ernst Chain, U. F. W. Ohnsorge, R. P. Sharma Journal of the Chemical Society Perkin Transactions 1 (1973)

158. BIOSYNTHESIS OF ERGOTAMINE BY CLAVICEPS PURPUREA (Fr.) TUL:

R. A. Bassett, E. B. Chain, K. Corbett.

Biochem. Journal (1973) 134, 1-10.

159. EFFECTS OF HEART WORK & INSULIN ON THE INCORPORATION OF (14 C) GLUCOSE INTO HEXOSE PHOSPHATES & URIDINE DIPHOSPHATE GLUCOSE IN NORMAL & DIABETIC PERFUSED RAT HEART:

Indrajit Das & Ernst B. Chain

Biochem. Society Transactions Vol. 1 (1973) 536th Meeting, London, 599.P

160. ABRUPT REOXYGENATION OF THE ANOXIC POTASSIUM-ARRESTED PERFUSED RAT HEART: A STUDY OF MYOCARDIAL ENZYME RELEASE:

D. J. Hearse, S. M. Humphrey, E. B. Chain

Journal of Molecular & Cellular Cardiology (1973) 5, 395-407.

161. THE EFFECT OF REOXYGENATION ON ENZYME RELEASE FROM THE ANOXIC ISOLATED PERFUSED RAT HEART:

D. J. Hearse, S. M. Humphrey, E. B. Chain

Biochem. Soc. Transactions 538th Meeting (1973), Birmingham, Vol. 1, .871. p

162. MYOCARDIAL ENZYME RELEASE UNDER CONDITIONS OF GRADED HYPOXIA:

Studies with the Isolated Perfused Rat Heart

D. J. Hearse, S. M. Humphrey, E. B. Chain

Biochem. Soc. Transactions (1973), 538th Meeting, Birmingham, Vol. 1, .869.p

163. BEITRAGE DES BIOCHEMIKERS ZUR ARZNEIMITTELFORSCHUNG:

E. Chain

Sonderdruck aus WIENER KLINISCHE WOCHENSCHRIFT 86 (1), 1-5 (1974) Schriftleiter: O. Kraupp und E. Deutsch.

164. MANIFESTATION EN L'HONNEUR DU DOYENF. TAYEAU:

E. B. Chain

Bordeaux Medical (1974) No. 16, 2443-2444.

165. STRUCTURE OF PSEUDO MONIC ACID, AN ANTIBIOTIC FROM PSEUDOMONAS FLUORESCENS:

E. B. Chain & Graham Mellow.

J. of the Chemical Soc. Chemical Communications (1974) 847-848.

166. THE EFFECTS OF CARDIOPLEGIA ON ADENOSINE TRIPHOSPHATE CONTENT & RECOVERY IN THE ISOLATED PERFUSED WORKING RAT HEART:

David J. Hearse, David A. Steward, Ernst B. Chain

Biochem. Soc. Trans., 2 (1974) 427.

167. RECOVERY FROM CARDIAC BYPASS & ELECTIVE CARDIAC ARREST:

The Metabolic Consequences of Various Cardioplegic Procedures in the Isolated Rat Heart.

David J. Hearse, David A. Steward, Ernst B. Chain

Circulation Research (September 1974) Vol. 35.

168. DIETARY FIBRE & STEROL METABOLISM IN THE RAT:

B. Morgan, Monique Heald, Sandra D. Atkin, J. Green, E. B. Chain Brit. J. Nutr. (1974) 32, 447-455.

169. REMINISCENCES OF SEVERO OCHOA FROM OUR OXFORD DAYS (REFLECTIONS ON BIOCHEMISTRY)

E. Chain

(1975)

170. CONCLUDING REMARKS:

Symposium on Food Science & Technology.

Sir Ernst Chain

Proc. Roy. Soc. London, B. (1975) Vol. 191, 195-198

171. THE PHARMACEUTICAL SCIENCES, GOVERNMENT & THE PEOPLE:

Sir Ernst Chain

Australian Journal of Pharmaceutical Sciences (1975), Vol. NS4, No. 1, 1-13.

172. FUSICOCCIN. PART 4. THE STRUCTURE OF FUSICOCCIN J+:

K. D. Barrow, D. H. R. Barton, Sir Ernst Chain, D. Bageenda-Kasujja, G. Mellows Journal of The Chemical Society. Perkin Transactions 1, (1975) 877-883.

173. PURIFICATION OF D-ALANINE CARBOXYPEPTIDASE FROM E SCHERICHIA COLI B:

M. Gorecki, Atara Bar-Eli, Yigal Burstein, A. Patchornik, E. B. Chain Biochem. J. (1975) 147, 131-137.

174. DIABETES AND THE SURVIVAL & RECOVERY OF THE ANOXIC MYOCARDIUM:

D. J. Hearse, D. A. Steward, E. B. Chain

J. Molecular & Cellular Cardiology (1975) Vol. 7, 397-415.

175. REFLECTIONS ON RESEARCH IN CHEMOTHERAPY:

Sir Ernst Chain

Chemotherapy (1976) 1, 7-13.

176. EFFECT OF HEART WORK & INSULIN ON THE INCORPORATION OF ¹4C GLUCOSE INTO HEXOSE PHOSPHATES, URIDINE DIPHOSPHATE GLUCOSE & GLYCOGEN IN THE NORMAL & INSULIN-DEFICIENT PERFUSED RAT HEART UNDER WORKING & NON-WORKING CONDITIONS:

Indrajit Das & Ernst B. Chain

J. Biochem (1976) 154, 765-772.

177. THE POSITION OF APPLIED RESEARCH IN NON-INDUSTRIAL LABORATORIES:

Chain Chapter I

Biotechnological Applications of Proteins & Enzymes

(1977) Academic Press, New York, S. Francisco & London.

178. PSEUDOMONIC ACID. PART I. THE STRUCTURE OF PSEU DOMONIC ACID A, A NOVEL ANTIBIOTIC PRODUCED BY PSEUDOMONAS FLUORESCENS:

Sir Ernst Chain & G. Mellows

J. Chem. Soc. Perkin Transactions I (1977) 294-309.

179. PSEUDOMONIC ACID: PART 3. STRUCTURE OF PSEUDOMONIC ACID B:

E. B. Chain, G. Mellows

J. of the Chemical Soc. Perkins Transactions 1 (1977) 318-322.

180. THE PENICILLIN DISCOVERY - PAST & PRESENT:

E. B. Chain

Japanese Journal of Antibiotics (1978) Vol. 31, No. 8, 493-507 (in Japanese)

181. THE EARLY YEARS OF THE PENICILLIN DISCOVERY:

E. Chain

TIPS (1979) inaugural issue.

Chemical Investigations on penicillin 1943-1945, sent in form of reports to the Committee for Penicillin Synthesis of the Medical Research Council.

(No copies of the following are available)

A. PEN Reports

(1) E. P. Abraham, E. Chain, W. Baker and R. Robinson - Pen 79, May 19th 1943 Further studies on the degradation of penicillin.

1. Effect of acid inactivation, acid hydrolysis and mercuric chloride on the optical activity of penicillin. 2. Penicillamine. 3. Penicillinic acid. 4. Degradation of penicillamine to penicillaminic acid. 5. Effect of ketene on penicillamine.

(2) E. P. Abraham, E. Chain, W. Baker and R. Robinson - Pen 88, July 30th 1943. Studies on the degradation of penicillin.

1. The presence of sulphur in the penicillin molecule. 2. The structure of penicillaminic acid. 3. The presence of a thiol group in penicillinamine and penicillamine.

(3) E. P. Abraham, E. Chain, W. Baker and R. Robinson - Pen 91, August 19th 1943. A discussion of the structure of penicillinic acid and its derivatives. The structure of penicillamine.

(4) E. P. Abraham, E. Chain, W. Baker and R. Robinson - Pen 99, Sept. 2nd 1943) Crystalline salts of penicillin.

(5) E. P. Abraham, E. Chain, W. Baker and R. Robinson - Pen 97, Sept. 16th 1943. Further studies on the degradation of penicillin.

Isopropyliden-penicillamine. Tosyl derivative of penicillamine. Aldehyde Fragment from penicillin hydrolysis.

(6) E. P. Abraham, E. Chain, W. Baker, J. W. Cornforth, R. N. Cornforth and R. Robinson - Pen 100, Oct. 4th 1943.

Synthesis of penicillamine.

(7) E. P. Abraham, E. Chain, W. Baker and R. Robinson - Pen 103, Oct. 23rd 1943. Further studies of the degradation of penicillin.

Formation of penilloaldehyde. Its oxidation to acid C8H13O3N.

Structure of penilloaldehyde. Structure of penillic acid.

Structures for penicillin. (oxazolene-thiazolidine and 2-lactam structures).

(8) E. P. Abraham, E. Chain, W. Baker and R. Robinson - Pen 109, Nov. 8th 1943) Further studies in the degradation of penicillin.

Structure of penillo-l-aldehyde. Synthesis of dihydropenilloaldehyde and the acid deriving from it by oxidation with silver oxide.

(9) E. P. Abraham, E. Chain, W. Baker and R. Robinson - Pen 111, Nov. 17th 1943. Further studies in the degradation of penicillin.

Synthesis of penilloic-l acid and penillo-l aldehyde.

B. CPS Reports

(1) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 1, Dec. 20th 1943. Constitution of penicillin.

(2) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 11, Jan. 4th 1944. Isopenillic acid.

(3) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 21, Feb. 2nd 1944. Mechanism of action of penicillinase.

(4) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 22, Feb. 26th 1944. Review of the structure of the penicillins in the light of recent evidence.

(5) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 29, March 18th 1944. Properties of some synthetic thiozolidines in relation to the structure of penicillin.

(6) D. P. Wilson, J. B. Jepson, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 26, March 16th 1944.

2-phenyl-4 ethoxymethyleneoxozolone and its condensation with 1-cysteine.

(7) J. P. Jepson, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 30, March 20th 1944.

2-Furyl -4-ethoxymethylene-oxazolone.

(8) J. F. W. McOmie, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 32, March 20th 1944.

The preparation of penicillamine from S-benzylpenicillamine.

(9) G. M. Robinson, E. P. Abraham, W. Baker, E. Chain and R. Robinson - March 27th 1944. 2-Styryl-4 ethoxymethylene-oxazolone

Formation of a bacteriostat of penicillin type.

(10) E. P. Abraham, E. Chain, W. Baker and R. Robinson - CPS 43, April 3rd 1944. Synthesis in the penicillin-II series, involving the use of dithiophenylacetic acid.

(11) J. W. Cornforth, D. H. Cornforth, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 57, April 2nd 1944.

Attempted synthesis of penillic acid. New synthesis of imidazoles and oxazoles.

(12) J. W. Cornforth, R. H. Cornforth, E. P. Abraham, E. Chain, W. Baker and R. Robinson - CPS 58, May 1st 1944.

2-hydroxy-5 propyloxazolone and its condensation with penicillamine.

(13) J. W. Cornforth, R. H. Cornforth, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 59, May 2nd 1944.

4-hydroxymethylene 2-n-amyloxazolone and its condensation with penicillamine. Possible synthesis in small yield of dihydropenicillin-1 or a stereoisomoride.

(14) F. E. King, S. G. Waley, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 68, May 30th 1944.

2-Benzylidene pseudo-oxazolone.

(15) J. W. Cornforth, R. H. Cornforth, M. J. S. Dewar, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 69, May 30th 1944.

PB -diethoxyalanine.

(16) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 71, June 1st 1944.

Synthesis of racemic decarboxy penillic II-acid, and racemic penillamine-II-hydrochloride.

(17) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 74, June 12th 1944.

Some further reactions of phenylthioacetylglycine. Phenyl-thioacetylalanine.

(18) J. P. Wilson, E. P. Abraham, W. Baker, E Chain and R. Robinson - CPS 76, June 14th 1944.

Derivatives of 4-Formyloxazolone.

(19) J. P. Wilson, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 92, June 24th 1944.

Transformations of benzoylaminocinnamhydrazide and remarks on the constitution of certain derivatives of hippuric acid.

(20) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 235, Aug. 26th 1944. Removal of the carbobenzoxy group from a 2-carbobenzoxy-amino-methylthiazolidine.

(21) R. J. S. Beer, F. E. King, E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 268, Sept. 19th 1944.

Dl-nor-penicilloic acid.

(22) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 271, Sept. 26th 1944. Structure of penicillin.

(23) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 342, Dec. 1st 1944. Synthesis of Intermediates (Penicilloic acid with unsubstituted amino group and its corresponding thio derivative).

(24) J. A. Barltrop, E. P. Abraham, W. Baker and R. Robinson - CPS 463, April 10th 1945. Thiazoline derivatives related to penicillamine.

(25) E. P. Abraham, W. Baker and E. Chain - CPS 554, July 1945.

The 5-lactam structure for the penicillins.

(26) E. P. Abraham, W. Baker, E. Chain and R. Robinson - CPS 648, Nov. 26th 1945. Synthetic penicillin in small yield.